ABSTRACT
Malignancy developing in the trophic ulcer of leprosy is no more a rarity. In four years period we detected seven cases of squamous cell carcinoma developing in the trophic ulcer in patients with lepromatous leprosy.
Subject(s)
Adolescent , Adult , Carcinoma, Squamous Cell/pathology , Cell Transformation, Neoplastic , Child , Foot Diseases/pathology , Humans , Leprosy, Lepromatous/complications , Male , Skin Neoplasms/pathology , Skin Ulcer/pathologyABSTRACT
Leprosy patients are protected from tetanus due to acquired natural immunity against tetanus. The incidence of tetanus in Leprosy is very low. A case of Indeterminate Leprosy developing tetanus following injury and terminating fatally is presented.
Subject(s)
Dapsone/therapeutic use , Humans , Knee Injuries/complications , Leprosy/complications , Male , Middle Aged , Seizures/complications , Skin Ulcer/complications , Tetanus/complicationsABSTRACT
Tetanus in lepromatous leprosy is rare and reported occasionally as case reports only. We present a case of lepromatous leprosy who succumbed to death due to rapidly progressing tetanus. The mechanism of protection from tetanus in leprosy is discussed.
Subject(s)
Adult , Dapsone/therapeutic use , Foot Diseases/complications , Humans , Leprosy, Lepromatous/complications , Male , Seizures/complications , Skin Ulcer/complications , Tetanus/complicationsABSTRACT
Development of malignancy in the trophic ulcer in leprosy is not previously believed rare. In India, less than a dozen cases are reported uptil now. We present a case of squamous cell carcinoma in trophic ulcer in leprosy patient because of its paucity in literature. Aetiopathogenesis of malignancy is discussed briefly.